Publikationen
_{Proteinevolution}

Bharat, T.; Tocheva, E.; Alva, V.: The cell envelope architecture of Deinococcus: HPI forms the S-layer and SlpA tethers the outer membrane to peptidoglycan. Proceedings of the National Academy of Sciences of the United States of America 120 (51), e2305338120 (2023)

Joiner, J.; Steinchen, W.; Mozer, N.; Kronenberger, T.; Bange, G.; Poso, A.; Wagner, S.; Hartmann, M.: HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids. The Journal of Biological Chemistry 299 (12), 105387 (2023)

Fonseca Lopez, F.; Miao, J.; Damjanovic, J.; Bischof, L.; Braun, M.; Ling, Y.; Hartmann, M.; Lin, Y.-S.; Kritzer, J.: Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders. Journal of Chemical Information and Modeling 63 (21), S. 6925 - 6937 (2023)

Smug, B.; Szczepaniak, K.; Riocha, E.; Dunin-Horkawicz, S.; Mostowy, R.: Ongoing shuffling of protein fragments diversifies core viral functions linked to interactions with bacterial hosts. Nature Communications 14 (1), 7460 (2023)

Steinebach, C.; Bricelj, A.; Murgai, A.; Sosič, I.; Bischof, L.; Ng, Y.; Heim, C.; Maiwald, S.; Proj, M.; Voget, R. et al.; Feller, F.; Košmrlj, J.; Sapozhnikova, V.; Schmidt, A.; Zuleeg, M.; Lemnitzer, P.; Mertins, P.; Hansen, F.; Gütschow, M.; Krönke, J.; Hartmann, M.: Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. Current Medicinal Chemistry 66 (21), S. 14513 - 14543 (2023)

Aubel, M.; Eicholt, L.; Bornberg-Bauer, E.; Lange, A.: Wie de novo entstandene Proteine im Labor exprimiert werden können. Biospektrum 29 (6), S. 629 - 632 (2023)

Kaminski, K.; Ludwiczak, J.; Pawlicki, K.; Alva, V.; Dunin-Horkawicz, S.: pLM-BLAST: distant homology detection based on direct comparison of sequence representations from protein language models. Bioinformatics 39 (10), btad579 (2023)

Zibat, A.; Zhang, X.; Dickmanns, A.; Stegmann, K.; Dobbelstein, A.; Alachram, H.; Soliwoda, R.; Salinas, G.; Görlich, D.; Kschischo, M. et al.; Wollnik, B.; Dobbelstein, M.: N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody. iScience 26 (10), 107786 (2023)

Fouks, B.; Harrison, M.; Mikhailova, A.; Marchal, E.; English, S.; Carruthers, M.; Jennings, E.; Pippel, M.; Attardo, G.; Benoit, B. et al.; Bornberg-Bauer, E.; Tobe, S.: Live-bearing cockroach genome reveals convergent evolutionary mechanisms linked to viviparity in insects and beyond. iScience 26 (10), 107832 (2023)

Martinez-Goikoetxea, M.; Lupas, A.: New protein families with hendecad coiled coils in the proteome of life. Journal of Structural Biology 215 (3), 108007 (2023)

Maksymenko, K.; Maurer, A.; Aghaallaei, N.; Barry, C.; Borbarán-Bravo, N.; Ullrich, T.; Dijkstra, T.; Hernandez-Alvarez, B.; Müller, P.; Lupas, A. et al.; Skokowa, J.; ElGamacy, M.: The design of functional proteins using tensorized energy calculations. Cell Reports Methods 3 (8), 100560 (2023)

Podobnik, M.; Singh, A.; Fu, Z.; Dooley, C.; Frohnhöfer, H.; Firlej, M.; Stednitz, S.; Elhabashy, H.; Weyand, S.; Weir, J. et al.; Lu, J.; Nüsslein-Volhard, C.; Irion, U.: kcnj13 regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution between Danio species. Development 150 (16), dev.201627 (2023)

Wu, Y.; Chen, K.-W.; Li, Y.-N.; Qiu, K.-Y.; Lu, G.; Shu, T.; Sun, T.-Y.; Hou , Z.-Q.; Wu, Y.-D.; Yu, L.-J.: Propeptide-Mediated Allosteric Regulation of Xylanase Xyl-1: An Integrated Experimental and Computational Analysis. Journal of Agricultural and Food Chemistry 71 (30), S. 11692 - 11703 (2023)

Braun, V.; Ratcliff, A.; Celia, H.; Buchanan, S.: Energization of Outer Membrane Transport by the ExbB ExbD Molecular Motor. Journal of Bacteriology 205 (6), e0003523 (2023)

Grandchamp, A.; Kühl, L.; Lebherz, M.; Brüggemann, K.; Parsch, J.; Bornberg-Bauer, E.: Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster. Genome Research 33 (6), S. 872 - 890 (2023)

Fuchs, A.: Specific, sensitive and quantitative protein detection by in-gel fluorescence. Nature Communications 14 (1), 2505 (2023)

Böhning, J.; Dobbelstein, A.; Sulkowski, N.; Eilers, K.; von Kügelgen, A.; Tarafder, A.; Peak-Chew, S.-Y.; Skehel, M.; Alva, V.; Filloux, A. et al.; Bharat, T.: Architecture of the biofilm-associated archaic Chaperone-Usher pilus CupE from Pseudomonas aeruginosa. PLoS Pathogens 19 (4), e1011177 (2023)

Heames, B.; Buchel, F.; Aubel, M.; Tretyachenko, V.; Loginov, D.; Novák, P.; Lange, A.; Bornberg-Bauer, E.; Hlouchová, K.: Experimental characterization of de novo proteins and their unevolved random-sequence counterparts. Nature Ecology & Evolution 7 (4), S. 570 - 580 (2023)

Iyengar, B.; Bornberg-Bauer, E.: Neutral models of de novo gene emergence suggest that gene evolution has a preferred trajectory. Molecular Biology and Evolution 40 (4), msad079 (2023)

von Kügelgen, A.; van Dorst, S.; Yamashita, K.; Sexton, D.; Tocheva, E.; Murshudov, G.; Alva, V.; Bharat, T.: Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans. Proceedings of the National Academy of Sciences of the United States of America 120 (16), e2215808120 (2023)