Publications
^{_{Protein Evolution}}

Lepore, S.; Kryshtafovyc, A.; Alahuthu, M.; Verasztó, H.; Bomble, Y.; Bufton, J.; Bullock, A.; Caba, C.; Cao, H.; Davies, O. et al.; Desfosses, A.; Dunne, M.; Fidelis, K.; Goulding, C.; Gurusaran, M.; Gutsche, I.; Harding, C.; Hartmann, M.; Hayes, C.; Joachimiak, A.; Leiman, P.; Loppnau, P.; Lovering , A.; Lunin, V.; Michalska, K.; Mir-Sanchis, I.; Mitra, A.; Mould, J.; Phillips , G.; Pinkas, D.; Rice, P.; Tong, Y.; Topf, M.; Walton, J.; Schwede, T.: Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins: Structure, Function, and Genetics 87 (12), S. 1037 - 1057 (2019)

Toledo-Patiño, S.; Chaubey, M.; Coles, M.; Höcker, B.: Reconstructing the Remote Origins of a Fold Singleton from a Flavodoxin-Like Ancestor. Biochemistry 58 (48), S. 4790 - 4793 (2019)

Lauer, J.; Segeletz, S.; Cezanne, A.; Guaitoli, G.; Raimondi, F.; Gentzel, M.; Alva, V.; Habeck, M.; Kalaidzidis, Y.; Ueffing, M. et al.; Lupas, A.; Gloeckner, C.; Zerial, M.: Auto-regulation of Rab5 GEF activity in Rabex5 by allosteric structural changes, catalytic core dynamics and ubiquitin binding. eLife 8, e46302 (2019)

Lederer, S.; Dijkstra, T.; Heskes, T.: Additive Dose Response Models: Defining Synergy. Frontiers in Pharmacology 10, 1384 (2019)

Afanasieva, E.; Chaudhuri, I.; Martin, J.; Hertle, E.; Ursinus, A.; Alva, V.; Hartmann, M.; Lupas, A.: Structural diversity of oligomeric β-propellers with different numbers of identical blades. eLife 8, e49853 (2019)

Morishima, T.; Krahl, A.-C.; Nasri, M.; Xu, Y.; Aghaallaei, N.; Findik, B.; Klimiankou, M.; Ritter, M.; Hartmann, M.; Gloeckner, C. et al.; Stefanczyk, S.; Lindner, C.; Oswald, B.; Bernhard, R.; Hähnel, K.; Hermanutz-Klein, U.; Ebinger, M.; Handgretinger, R.; Casadei, N.; Welte, K.; Andre, M.; Müller, P.; Bajoghli, B.; Skokowa, J.: LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. Blood 134 (14), S. 1159 - 1175 (2019)

Connah, L.; Truffault, V.; Truffault, V.; Platas-Iglesias, C.; Angelovski, G.: Investigations into the effects of linker length elongation on the behaviour of calcium-responsive MRI probes. Dalton Transactions 48 (36), S. 13546 - 13554 (2019)

Brault, M.; Petit, J.; Immel, F.; Nicolas, W.; Glavier, M.; Brocard, L.; Gaston, A.; Fouché, M.; Hawkins, T.; Crowet, J.-M. et al.; Grison, M.; Germain, V.; Rocher, M.; Kraner, M.; Alva, V.; Claverol, S.; Paterlini, A.; Helariutta, Y.; Deleu, M.; Lins, L.; Tilsner, J.; Bayer, E.: Multiple C2 domains and transmembrane region proteins (MCTPs) tether membranes at plasmodesmata. EMBO Reports 20 (8), e47182 (2019)

Ludwiczak, J.; Winski, A.; Szczepaniak , A.; Alva, V.; Dunin-Horkawicz, S.: DeepCoil: a fast and accurate prediction of coiled-coil domains in protein sequences. Bioinformatics 35 (16), S. 2790 - 2795 (2019)

Alva, V.; Lupas, A.: Histones Predate the Split Between Bacteria and Archaea. Bioinformatics 35 (14), S. 2349 - 2353 (2019)

Heim, C.; Pliatsika, D.; Mousavizadeh, F.; Bär, K.; Hernandez Alvarez, B.; Giannis, A.; Hartmann, M.: De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives. Journal of Medicinal Chemistry 62 (14), S. 6615 - 6629 (2019)

Hernandez Alvarez, B.; Bassler, J.; Lupas, A.: Structural diversity of coiled coils in protein fibers of the bacterial cell envelope. International Journal of Medical Microbiology 309 (5), S. 351 - 358 (2019)

Wissig, J.; Grischin, J.; Bassler, J.; Schubert, C.; Friedrich, T.; Bähre, H.; Schultz, J.; Unden, G.: CyaC, a redox-regulated adenylate cyclase of Sinorhizobium meliloti with a quinone responsive diheme-B membrane anchor domain. Molecular Microbiology 112 (1), S. 16 - 28 (2019)

Finkbeiner, M.; Grischin, J.; Seth, A.; Schultz, J.: In search of a function for the membrane anchors of class IIIa adenylate cyclases. International Journal of Medical Microbiology 309 (3-4), S. 245 - 251 (2019)

Walter, J.; Selim, K.; Leganés, F.; Fernández-Piñas, F.; Vothknecht, U.; Forchhammer, K.; Aro, E.-M.; Gollan, P.: A novel Ca 2+-binding protein influences photosynthetic electron transport in Anabaena sp. PCC 7120. Biochimica et Biophysica Acta, Bioenergetics 1860 (6), S. 519 - 532 (2019)

an den Brand, J.; Dijkstra, T.; Wetzels, J.; Stengel, B.; Metzger, M.; Blankestijn, P.; Lambers Heerspink, H.; Gansevoort, R.: Predicting kidney failure from longitudinal kidney function trajectory: A comparison of models. PLoS One 14 (5), e0216559 (2019)

ElGamacy, M.; Riss, M.; Zhu, H.; Truffault, V.; Coles, M.: Mapping Local Conformational Landscapes of Proteins in Solution. Structure 27 (5), S. 853 - 865 (2019)

Fuchs, A.; Hartmann, M.: On the Origins of Symmetry and Modularity in the Proteasome Family: Symmetry Transitions are Pivotal in the Evolution and Functional Diversification of Self-Compartmentalizing Proteases. Bioessays 41 (5), e1800237 (2019)

Ludwiczak, J.; Winski, A.; Marinho da Silva Neto, A.; Szczepaniak, K.; Alva, V.; Dunin-Horkawicz, S.: PiPred: a deep-learning method for prediction of π-helices in protein sequences. Scientific Reports 9, 6888 (2019)

Adlakha, J.; Karamichali, I.; Sangwallek, J.; Deiss, S.; Bär, K.; Coles, M.; Hartmann, M.; Lupas, A.; Hernandez Alvarez, B.: Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles. Structure 27 (3), S. 464 - 475 (2019)