Publications
^{_{Protein Evolution}}

Kuchta, R.; Heim, C.; Herrmann, A.; Maiwald, S.; Ng, Y.; Sosič, I.; Keuler, T.; Krönke, J.; Gütschow, M.; Hartmann, M. et al.; Steinebach, C.: Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC Chemical Biology 4 (3), S. 229 - 234 (2023)

Aubel, M.; Bornberg-Bauer, E.: Introducing creative destruction as a mechanism in protein evolution. Proceedings of the National Academy of Sciences of the United States of America 120 (6), e2220460120 (2023)

Mantovani, O.; Haffner, M.; Selim, K.; Hagemann, M.; Forchhammer, K.: Roles of second messengers in the regulation of cyanobacterial physiology: the carbon-concentrating mechanism and beyond. microLife Epub ahead, uqad008 (2023)

Selim, K.; Haffner, M.; Mantovani, O.; Albrecht, R.; Zhu, H.; Hagemann, M.; Forchhammer, K.; Hartmann, M.: Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA. Proceedings of the National Academy of Sciences of the United States of America 120 (8), e2205882120 (2023)

Bakker, R.; Ellers, J.; Roelofs, D.; Vooijs, R.; Dijkstra, T.; van Gestel, C.; Hoedjes, K.: Combining time-resolved transcriptomics and proteomics data for Adverse Outcome Pathway refinement in ecotoxicology. Science of the Total Environment 869, 161740 (2023)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron. Biochemical and Biophysical Research Communications 646, S. 30 - 35 (2023)

Martinez-Goikoetxea, M.; Lupas, A.: A conserved motif suggests a common origin for a group of proteins involved in the cell division of Gram-positive bacteria. PLoS One 18 (1), e0273136 (2023)

Yoshimoto, S.; Aoki, S.; Ohara, Y.; Ishikawa, M.; Suzuki, A.; Linke, D.; Lupas, A.; Hori, K.: Identification of the adhesive domain of AtaA from Acinetobacter sp. Tol 5 and its application in immobilizing Escherichia coli. Frontiers in Bioengineering and Biotechnology 10, e1095057 (2023)

Coban, A.; Bornberg-Bauer, E.; Kemena, C.: Domain Evolution of Vertebrate Blood Coagulation Cascade Proteins. Journal of Molecular Evolution: the Journal of the International Society of Molecular Evolution 90 (6), S. 418 - 428 (2022)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochemical and Biophysical Research Communications 637, S. 66 - 72 (2022)

Krasavin, M.; Adamchik, M.; Bubyrev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Zhmurov, P.; Bunev, A.; Hartmann, M.: Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines. European Journal of Medicinal Chemistry 246, 114990 (2022)

Krasavin, M.; Bubyrev, A.; Kazantsev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Dar'in, D.; Hartmann, M.; Brunev, A.: Replacing the phthalimide core in thalidomide with benzotriazole. Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), S. 527 - 530 (2022)

Stahlecker, J.; Klett, T.; Schwer, M.; Jaag, S.; Dammann, M.; Ernst, L.; Braun, M.; Zimmermann, M.; Kramer, M.; Lämmerhofer, M. et al.; Stehle, T.; Coles, M.; Boeckler, F.: Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C. RSC Medicinal Chemistry 13 (12), S. 1575 - 1586 (2022)

Barkhatova, D.; Zhukovsky, D.; Heim, C.; Maiwald, S.; Hartmann, M.; Krasavin, M.: Synthesis of novel glutarimide derivatives via the Ugi multicomponent reaction: affinity towards the E3 ubiquitin ligase substrate receptor Cereblon. Mendeleev Communications 32 (6), S. 747 - 749 (2022)

Dammann, M.; Stahlecker, J.; Zimmermann, M.; Klett, T.; Rotzinger, K.; Kramer, M.; Coles, M.; Stehle, T.; Boeckler, F.: Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes. Journal of Medicinal Chemistry 65 (21), S. 14539 - 14552 (2022)

Eenink, B.; Kaminski, T.; Bornberg-Bauer, E.; Jose, J.; Hollfelder, F.; van Loo, B.: Vector redesign and in-droplet cell-growth improves enrichment and recovery in live Escherichia coli. Microbial Biotechnology 15 (11), S. 2845 - 2853 (2022)

Escobedo, A.; Piccirillo, J.; Aranda, J.; Diercks, T.; Mateos, B.; Garcia-Cabau, C.; Sánchez-Navarro, M.; Topal, B.; Biesaga, M.; Staby, L. et al.; Kragelund, B.; García, J.; Millet, O.; Orozco, M.; Coles, M.; Crehuet, R.; Salvatella, X.: A glutamine-based single α-helix scaffold to target globular proteins. Nature Communications 13 (1), 7073 (2022)

Berger, J.; Legendre, F.; Zelosko, K.-M.; Harrison, M.; Grandcolas, P.; Bornberg-Bauer, E.; Fouks, B.: Eusocial Transition in Blattodea: Transposable Elements and Shifts of Gene Expression. Genes 13 (11), 1948 (2022)

Singh, J.; Elhabashy, H.; Muthukottiappan, P.; Stepath, M.; Eisenacher, M.; Kohlbacher, O.; Gieselmann, V.; Winter, D.: Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo. Nature Communications 13 (1), 6212 (2022)

Srivastava, A.; Selim, K.: Inheritable nanotubes boost bioimaging and photovoltaics in cyanobacteria. Nature Nanotechnology 17 (10), S. 1046 - 1047 (2022)