Publikationen
_{Molekülerkennung und Katalyse}

Kumar Golla, V.; Benz, R.; Kleinekathöfer, U.; Piselli, C.: Glyphosate uptake pathway across the outer membrane of Pseudomonas aeruginosa. Biochimica et Biophysica Acta (BBA) - General Subjects 1870 (11), 130991 (2026)

Hartmann, M.; Hernandez Alvarez, B.; Martinez-Goikoetxea, M.; Lupas, A.: Building coiled coils with polar cores. Protein Science 35 (10), e70807 (2026)

Coles, M.; Ewers, C.; Albrecht, R.; Martinez-Goikoetxea, M.; Orlowska, M.; Martin, J.; Lupas, A.; Hartmann, M.; Dunin-Horkawicz, S.: Conformational diversity in poly-HAMP arrays and its implications for signal transduction. Protein Science 35 (9), e70743 (2026)

Müller, T.; Stahlecker, F.; Roganowicz, K.; Samir, S.; Weiss, G.; Coles, M.; Selim, K.: The calcium-binding protein CSE links Ca2+ signaling with cell-cell communication in cyanobacteria. The EMBO Journal 45 (18), S. 6630 - 6654 (2026)

Adamlje, B.; Tomašič, T.; Steinebach, C.; Ebeling, S.; Herrmann, A.; Hartmann, M.; Horner, J.; Bhadresha, K.; Chau, C.; Figg, W. et al.; Sosič, I.; Cotman, A.: Fluorinated Aminopiperidones as Non-Glutarimide Thalidomide Analogs: Stereodivergent Synthesis and Validation. ChemMedChem 21 (13), e70360 (2026)

Hartmann, M.: Writing the CRBN degron. Nature Chemical Biology 22 (5), S. 683 - 684 (2026)

Maksutova, A.; Geiger, T.; Cianni, L.; Pieńkowska, D.; Gerhartz, J.; Read, L.; Bricelj, A.; Herrmann, A.; Nelles, M.; Ng, Y. et al.; Hartmann, M.; Krönke, J.; Sosič, I.; Nowak, R.; Gütschow , M.; Steinebach, C.: A Facile Protocol for C(sp2)-C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands. ChemMedChem 21 (4), e202500929 (2026)

Kretsch, R.; Albrecht, R.; Andersen, E.; Chen, H.-A.; Chiu, W.; Das, R.; Gezelle, J.; Hartmann, M.; Höbartner, C.; Hu, Y. et al.; Jadhav, S.; Johnson, P.; Jones, C.; Koirala, D.; Kristoffersen, E.; Largy, E.; Lewicka, A.; Mackereth, C.; Marcia, M.; Nigro, M.; Ohja, M.; Piccirilli, J.; Rice, P.; Shin, H.; Steckelberg, A.-L.; Su, Z.; Srivastava, Y.; Wang, L.; Wu, Y.; Xie, J.; Zwergius, N.; Moult, J.; Kryshtafovych, A.: Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers. Proteins: Structure, Function, and Bioinformatics 94 (1), S. 51 - 78 (2026)

Levashova, E.; Bischof, L.; Bunev, A.; Sapegin , A.; Grygor'eva, O.; Kudinev, A.; Ebeling, S.; Tatarinov, I.; Dar'in, D.; Kantin, G. et al.; Hartmann, M.; Kalinin, S.: Extending the chemical space of glutarimide-based cereblon ligands through an efficient Rh(II)-catalyzed X-H insertion reaction. European Journal of Medicinal Chemistry 301, 118235 (2026)

Hu, Y.; Schwab, S.; Qiu, K.; Zhang, Y.; Bär, K.; Reichle, H.; Panzera, A.; Lupas, A.; Hartmann, M.; Dame, R. et al.; Alva, V.; Hernandez Alvarez, B.: DNA Wrapping by a Tetrameric Bacterial Histone. Nature Communications 16, 11108 (2025)

Wagner, B.; Steuer-Lodd, K.; Geibel, C.; Stadelmann, A.; Rapp, J.; Link, H.; Schramm, T.; Boodaghian, N.; Hsiao, A.; Nussbaum, E. et al.; Grenzendorfer, H.-P.; Albrecht, R.; Hartmann, M.; Forchhammer, K.; Selim, K.; Hughes, C.; Petras, D.: Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding. Proceedings of the National Academy of Sciences of the United States of America 122 (48), e2509468122 (2025)

Maksymenko, K.; Hatskovska, V.; Coles, M.; Aghaallaei , N.; Pashkovskaia, N.; Borbarán-Bravo, N.; Pilz, M.; Bucher, P.; Volz, M.; Pereira, J. et al.; Hartmann, M.; Tabatabai, G.; Feucht, J.; Liebau, S.; Müller, P.; Lupas, A.; Skokowa, J.; ElGamacy, M.: A Complementarity-Based Approach to De Novo Binder Design. Advanced Science 12 (13), e02015 (2025)

Wittenburg, S.; Zuleeg, M.; Peter, K.; Lemnitzer, P.; Voget, R.; Bricelj, A.; Gobec, M.; Dierlamm, N.; Braun, M.; Geiger, T. et al.; Heim, C.; Stakemeier, A.; Wagner, K.; Nowak, R.; Hartmann, M.; Sosič, I.; Gütschow, M.; Krönke, J.; Steinebach, C.: Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability. Journal of Medicinal Chemistry 68 (15), S. 15711 - 15737 (2025)

Hartmann, M.: Expanding the reach of molecular glue degraders. Science 389 (6755), S. 32 - 33 (2025)

Boudrioua, A.; Joiner, J.; Grin, I.; Kronenberger, T.; Korotkov, V.; Steinchen, W.; Kohler, A.; Schminke, S.; Schulte, J.-C.; Pietsch, M. et al.; Naini, A.; Kalverkamp, S.; Hotop, S.-K.; Coyle, T.; Piselli, C.; Coles, M.; Rox, K.; Marschal, M.; Bange, G.; Flieger, A.; Poso, A.; Brönstrup, M.; Hartmann, M.; Wagner, S.: Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity. Science Advances 11 (15), eadr5235 (2025)

Ananevaa, A.; Kantin, G.; Dar’in, D.; Bunev, A.; Ebeling, S.; Herrmann, A.; Hartmann, M.; Kalinin, S.; Bakulina, O.: Catalytic Castagnoli–Cushman reaction-based synthesis of tetrahydroisoquinolone–glutarimide dyads and their evaluation as potential cereblon ligands. Mendeleev Communications 35 (3), S. 285 - 288 (2025)

Piselli, C.: How to isolate channel-forming membrane proteins using the E. coli expression system. Nature Protocols 20 (2), S. 462 - 479 (2025)

Khuzhakhmetova, L.; Ananeva, A.; Gantin, G.; Dar’in, D.; Bunev, A.; Ebeling, S.; Herrmann, A.; Hartmann, M.; Kalinin, S.; Bakulina, O.: Synthesis of α-(azidomethyl)glutarimide and its applicationin construction of potential Cereblon ligands via the CuAAC reaction. Mendeleev Communications 35 (1), S. 69 - 72 (2025)

Ullrich, T.; Klimenkova, O.; Pollmann, C.; Lasram, A.; Hatskovska, V.; Maksymenko, K.; Milijaš-Jotić, M.; Schenk, L.; Lengerke, C.; Hartmann, M. et al.; Piehler, J.; Skokowa, J.; ElGamacy, M.: A Strategy to Design Protein-based Antagonists Against Type I Cytokine Receptors. PLOS Biology (angenommen)

Schwab, S.; Hu, Y.; van Erp, B.; Kajili, M.; Hartmann, M.; Hernandez-Alvarez, B.; Alva, V.; Boyle, A.; Dame, R.: Histones and histone variant families in prokaryotes. Nature Communications 15 (1), 7950 (2024)