Publikationen
_{^{Molekülerkennung und Katalyse}}

Kuchta, R.; Heim, C.; Herrmann, A.; Maiwald, S.; Ng, Y.; Sosič, I.; Keuler, T.; Krönke, J.; Gütschow, M.; Hartmann, M. et al.; Steinebach, C.: Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC Chemical Biology 4 (3), S. 229 - 234 (2023)

Mantovani, O.; Haffner, M.; Selim, K.; Hagemann, M.; Forchhammer, K.: Roles of second messengers in the regulation of cyanobacterial physiology: the carbon-concentrating mechanism and beyond. microLife Epub ahead, uqad008 (2023)

Selim, K.; Haffner, M.; Mantovani, O.; Albrecht, R.; Zhu, H.; Hagemann, M.; Forchhammer, K.; Hartmann, M.: Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA. Proceedings of the National Academy of Sciences of the United States of America 120 (8), e2205882120 (2023)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron. Biochemical and Biophysical Research Communications 646, S. 30 - 35 (2023)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochemical and Biophysical Research Communications 637, S. 66 - 72 (2022)

Krasavin, M.; Adamchik, M.; Bubyrev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Zhmurov, P.; Bunev, A.; Hartmann, M.: Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines. European Journal of Medicinal Chemistry 246, 114990 (2022)

Krasavin, M.; Bubyrev, A.; Kazantsev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Dar'in, D.; Hartmann, M.; Brunev, A.: Replacing the phthalimide core in thalidomide with benzotriazole. Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), S. 527 - 530 (2022)

Barkhatova, D.; Zhukovsky, D.; Heim, C.; Maiwald, S.; Hartmann, M.; Krasavin, M.: Synthesis of novel glutarimide derivatives via the Ugi multicomponent reaction: affinity towards the E3 ubiquitin ligase substrate receptor Cereblon. Mendeleev Communications 32 (6), S. 747 - 749 (2022)

Iskhakova, Z.; Zhuravleva, D.; Heim, C.; Hartmann, M.; Laykov , A.; Forchhammer, K.; Kayumov, A.: PotN represents a novel energy-state sensing PII subfamily, occurring in firmicutes. The FEBS Journal 289 (17), S. 5305 - 5321 (2022)

Braun, V.; Hartmann, M.; Hantke, K.: Transcription regulation of iron carrier transport genes by ECF sigma factors through signaling from the cell surface into the cytoplasm. FEMS Microbiology Reviews 46 (4), fuac010 (2022)

Heim, C.; Hartmann, M.: High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 78 (3), S. 290 - 298 (2022)

Hartmann, M.: A complex struggle for direction. Nature Chemical Biology 18 (2), S. 119 - 120 (2022)

Alexander, L.; Lepore, R.; Kryshtafovych, A.; Adamopoulos, A.; Alahuhta, M.; Arvin, A.; Bomble, Y.; Böttcher, B.; Breyton, C.; Chiarini, A. et al.; Chinnam, N.; Chiu, W.; Fidelis, K.; Grinter, R.; Gupta, G.; Hartmann, M.; Hayes, C.; Heidebrecht, T.; Ilari, A.; Joachimiak, A.; Kim, Y.; Linares, R.; Lovering, A.; Lunin, V.; Lupas, A.; Makbul, C.; Michalska, K.; Moult, J.; Mukherjee, P.; Nutt, W.; Oliver, S.; Perrakis, A.; Stols, L.; Tainer, J.; Topf, M.; Tsutakawa, S.; Valdivia-Delgado, M.; Schwede, T.: Target highlights in CASP14: Analysis of models by structure providers. Proteins: Structure, Function, and Genetics 89 (12), S. 1647 - 1672 (2021)

Kryshtafovych, A.; Moult, J.; Albrecht, R.; Chang, G.; Cao, K.; Fraser, A.; Greenfield, J.; Hartmann, M.; Herzberg, O.; Joosts, I. et al.; Leiman, P.; Linden, S.; Lupas, A.; Nelson, D.; Rees, S.; Shang, X.; Sokolova, M.; Tidow, H.: Computational models in the service of X-ray and cryo-electron microscopy structure determination. Proteins: Structure, Function, and Bioinformatics 89 (12), S. 1633 - 1646 (2021)

Maiwald, S.; Heim, C.; Hernandez Alvarez, B.; Hartmann, M.: Correction to "Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay". ACS Medicinal Chemistry Letters 13 (1), S. 148 - 149 (2021)

Millán, C.; Keegan, R.; Pereira, J.; Sammito, M.; Simpkin, A.; McCoy, A.; Lupas, A.; Hartmann, M.; Rigden, D.; Read, R.: Assessing the utility of CASP14 models for molecular replacement. Proteins: Structure, Function, and Bioinformatics 89 (12), S. 1752 - 1769 (2021)

Pereira, J.; Simpkin, A.; Hartmann, M.; Rigden, D.; Keegan, R.; Lupas, A.: High-accuracy protein structure prediction in CASP14. Proteins: Structure, Function, and Bioinformatics 89 (12), S. 1687 - 1699 (2021)

Selim, K.; Haffner, M.; Burkhardt, M.; Mantovani, O.; Neumann, N.; Albrecht, R.; Seifert, R.; Krüger, L.; Stülke, J.; Hartmann, M. et al.; Hagemann, M.; Forchhammer, K.: Diurnal metabolic control in cyanobacteria requires perception of second messenger signaling molecule c-di-AMP by the carbon control protein SbtB. Science Advances 7 (50), eabk0568 (2021)

Lupas, A.; Pereira, J.; Alva, V.; Merino, F.; Coles, M.; Hartmann, M.: The breakthrough in protein structure prediction. Biochemical Journal 478 (10), S. 1885 - 1890 (2021)

Fuchs, A.; Ammelburg, M.; Martin, J.; Schmitz, R.; Hartmann, M.; Lupas, A.: Archaeal Connectase is a specific and efficient protein ligase related to proteasome β subunits. Proceedings of the National Academy of Sciences of the United States of America 118 (11), e2017871118 (2021)