Publications
Molecular Recognition and Catalysis

Journal Article (61)

1.
Journal Article
Hartmann, M.: TRIM for Tissue Specificity. ACS Medicinal Chemistry Letters 15 (1), pp. 4 - 5 (2024)
2.
Journal Article
Alexander, L.; Durairaj, J.; Kryshtafovych, A.; Abriata, L.; Bayo, Y.; Bhabha, G.; Breyton, C.; Caulton, S.; Chen, J.; Degroux, S. et al.; Ekiert, D.; Erlandsen, B.; Freddolino, P.; Gilzer, D.; Greening, C.; Grimes, J.; Grinter, R.; Gurusaran, M.; Hartmann, M.; Hitchman, C.; Keown, J.; Kropp, A.; Kursula, P.; Lovering, A.; Lemaitre, B.; Lia, A.; Liu, S.; Logotheti, M.; Lu, S.; Markússon, S.; Miller, M.; Minasov, G.; Niemann, H.; Opazo, F.; Phillips jr, G.; Davies, O.; Rommelaere, S.; Rosas-Lemus, M.; Roversi, P.; Satchell, K.; Smith, N.; Wilson, M.; Wu, K.-L.; Xia, X.; Xiao, H.; Zhang, W.; Zhou, Z.; Fidelis, K.; Topf, M.; Moult, J.; Schwede, T.: Protein target highlights in CASP15: Analysis of models by structure providers. Proteins: Structure, Function, and Bioinformatics 91 (12), pp. 1571 - 1599 (2023)
3.
Journal Article
Joiner, J.; Steinchen, W.; Mozer, N.; Kronenberger, T.; Bange, G.; Poso, A.; Wagner, S.; Hartmann, M.: HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids. The Journal of Biological Chemistry 299 (12), 105387 (2023)
4.
Journal Article
Fonseca Lopez, F.; Miao, J.; Damjanovic, J.; Bischof, L.; Braun, M.; Ling, Y.; Hartmann, M.; Lin, Y.-S.; Kritzer, J.: Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders. Journal of Chemical Information and Modeling 63 (21), pp. 6925 - 6937 (2023)
5.
Journal Article
Steinebach, C.; Bricelj, A.; Murgai, A.; Sosič, I.; Bischof, L.; Ng, Y.; Heim, C.; Maiwald, S.; Proj, M.; Voget, R. et al.; Feller, F.; Košmrlj, J.; Sapozhnikova, V.; Schmidt, A.; Zuleeg, M.; Lemnitzer, P.; Mertins, P.; Hansen, F.; Gütschow, M.; Krönke, J.; Hartmann, M.: Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. Current Medicinal Chemistry 66 (21), pp. 14513 - 14543 (2023)
6.
Journal Article
Kuchta, R.; Heim, C.; Herrmann, A.; Maiwald, S.; Ng, Y.; Sosič, I.; Keuler, T.; Krönke, J.; Gütschow, M.; Hartmann, M. et al.; Steinebach, C.: Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC Chemical Biology 4 (3), pp. 229 - 234 (2023)
7.
Journal Article
Mantovani, O.; Haffner, M.; Selim, K.; Hagemann, M.; Forchhammer, K.: Roles of second messengers in the regulation of cyanobacterial physiology: the carbon-concentrating mechanism and beyond. microLife 4, uqad008 (2023)
8.
Journal Article
Selim, K.; Haffner, M.; Mantovani, O.; Albrecht, R.; Zhu, H.; Hagemann, M.; Forchhammer, K.; Hartmann, M.: Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA. Proceedings of the National Academy of Sciences of the United States of America 120 (8), e2205882120 (2023)
9.
Journal Article
Selim, K.; Zimmer, E.: SbtB: der fehlende Sensor für anorganischen Kohlenstoff in Cyanobakterien. Biospektrum 29 (2), pp. 140 - 143 (2023)
10.
Journal Article
Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron. Biochemical and Biophysical Research Communications 646, pp. 30 - 35 (2023)
11.
Journal Article
Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochemical and Biophysical Research Communications 637, pp. 66 - 72 (2022)
12.
Journal Article
Krasavin, M.; Adamchik, M.; Bubyrev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Zhmurov, P.; Bunev, A.; Hartmann, M.: Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines. European Journal of Medicinal Chemistry 246, 114990 (2022)
13.
Journal Article
Krasavin, M.; Bubyrev, A.; Kazantsev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Dar'in, D.; Hartmann, M.; Brunev, A.: Replacing the phthalimide core in thalidomide with benzotriazole. Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), pp. 527 - 530 (2022)
14.
Journal Article
Barkhatova, D.; Zhukovsky, D.; Heim, C.; Maiwald, S.; Hartmann, M.; Krasavin, M.: Synthesis of novel glutarimide derivatives via the Ugi multicomponent reaction: affinity towards the E3 ubiquitin ligase substrate receptor Cereblon. Mendeleev Communications 32 (6), pp. 747 - 749 (2022)
15.
Journal Article
Iskhakova, Z.; Zhuravleva, D.; Heim, C.; Hartmann, M.; Laykov , A.; Forchhammer, K.; Kayumov, A.: PotN represents a novel energy-state sensing PII subfamily, occurring in firmicutes. The FEBS Journal 289 (17), pp. 5305 - 5321 (2022)
16.
Journal Article
Braun, V.; Hartmann, M.; Hantke, K.: Transcription regulation of iron carrier transport genes by ECF sigma factors through signaling from the cell surface into the cytoplasm. FEMS Microbiology Reviews 46 (4), fuac010 (2022)
17.
Journal Article
Heim, C.; Hartmann, M.: High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 78 (3), pp. 290 - 298 (2022)
18.
Journal Article
Hartmann, M.: A complex struggle for direction. Nature Chemical Biology 18 (2), pp. 119 - 120 (2022)
19.
Journal Article
Alexander, L.; Lepore, R.; Kryshtafovych, A.; Adamopoulos, A.; Alahuhta, M.; Arvin, A.; Bomble, Y.; Böttcher, B.; Breyton, C.; Chiarini, A. et al.; Chinnam, N.; Chiu, W.; Fidelis, K.; Grinter, R.; Gupta, G.; Hartmann, M.; Hayes, C.; Heidebrecht, T.; Ilari, A.; Joachimiak, A.; Kim, Y.; Linares, R.; Lovering, A.; Lunin, V.; Lupas, A.; Makbul, C.; Michalska, K.; Moult, J.; Mukherjee, P.; Nutt, W.; Oliver, S.; Perrakis, A.; Stols, L.; Tainer, J.; Topf, M.; Tsutakawa, S.; Valdivia-Delgado, M.; Schwede, T.: Target highlights in CASP14: Analysis of models by structure providers. Proteins: Structure, Function, and Genetics 89 (12), pp. 1647 - 1672 (2021)
20.
Journal Article
Kryshtafovych, A.; Moult, J.; Albrecht, R.; Chang, G.; Cao, K.; Fraser, A.; Greenfield, J.; Hartmann, M.; Herzberg, O.; Joosts, I. et al.; Leiman, P.; Linden, S.; Lupas, A.; Nelson, D.; Rees, S.; Shang, X.; Sokolova, M.; Tidow, H.: Computational models in the service of X-ray and cryo-electron microscopy structure determination. Proteins: Structure, Function, and Bioinformatics 89 (12), pp. 1633 - 1646 (2021)
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