Publikationen von MD Hartmann
Alle Typen
Zeitschriftenartikel (67)
1.
Zeitschriftenartikel
270, 116328 (2024)
Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. European Journal of Medicinal Chemistry 2.
Zeitschriftenartikel
15 (1), S. 4 - 5 (2024)
TRIM for Tissue Specificity. ACS Medicinal Chemistry Letters 3.
Zeitschriftenartikel
91 (12), S. 1571 - 1599 (2023)
Protein target highlights in CASP15: Analysis of models by structure providers. Proteins: Structure, Function, and Bioinformatics 4.
Zeitschriftenartikel
299 (12), 105387 (2023)
HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids. The Journal of Biological Chemistry 5.
Zeitschriftenartikel
63 (21), S. 6925 - 6937 (2023)
Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders. Journal of Chemical Information and Modeling 6.
Zeitschriftenartikel
66 (21), S. 14513 - 14543 (2023)
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. Current Medicinal Chemistry 7.
Zeitschriftenartikel
4 (3), S. 229 - 234 (2023)
Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC Chemical Biology 8.
Zeitschriftenartikel
120 (8), e2205882120 (2023)
Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA. Proceedings of the National Academy of Sciences of the United States of America 9.
Zeitschriftenartikel
646, S. 30 - 35 (2023)
Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron. Biochemical and Biophysical Research Communications 10.
Zeitschriftenartikel
637, S. 66 - 72 (2022)
Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochemical and Biophysical Research Communications 11.
Zeitschriftenartikel
246, 114990 (2022)
Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines. European Journal of Medicinal Chemistry 12.
Zeitschriftenartikel
37 (1), S. 527 - 530 (2022)
Replacing the phthalimide core in thalidomide with benzotriazole. Journal of Enzyme Inhibition and Medicinal Chemistry 13.
Zeitschriftenartikel
32 (6), S. 747 - 749 (2022)
Synthesis of novel glutarimide derivatives via the Ugi multicomponent reaction: affinity towards the E3 ubiquitin ligase substrate receptor Cereblon. Mendeleev Communications 14.
Zeitschriftenartikel
289 (17), S. 5305 - 5321 (2022)
PotN represents a novel energy-state sensing PII subfamily, occurring in firmicutes. The FEBS Journal 15.
Zeitschriftenartikel
46 (4), fuac010 (2022)
Transcription regulation of iron carrier transport genes by ECF sigma factors through signaling from the cell surface into the cytoplasm. FEMS Microbiology Reviews 16.
Zeitschriftenartikel
78 (3), S. 290 - 298 (2022)
High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 17.
Zeitschriftenartikel
18 (2), S. 119 - 120 (2022)
A complex struggle for direction. Nature Chemical Biology 18.
Zeitschriftenartikel
89 (12), S. 1647 - 1672 (2021)
Target highlights in CASP14: Analysis of models by structure providers. Proteins: Structure, Function, and Genetics 19.
Zeitschriftenartikel
89 (12), S. 1633 - 1646 (2021)
Computational models in the service of X-ray and cryo-electron microscopy structure determination. Proteins: Structure, Function, and Bioinformatics 20.
Zeitschriftenartikel
13 (1), S. 148 - 149 (2021)
Correction to "Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay". ACS Medicinal Chemistry Letters