Publications
^{_{Protein Evolution}}

Coban, A.; Bornberg-Bauer, E.; Kemena, C.: Domain Evolution of Vertebrate Blood Coagulation Cascade Proteins. Journal of Molecular Evolution: the Journal of the International Society of Molecular Evolution 90 (6), pp. 418 - 428 (2022)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochemical and Biophysical Research Communications 637, pp. 66 - 72 (2022)

Krasavin, M.; Adamchik, M.; Bubyrev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Zhmurov, P.; Bunev, A.; Hartmann, M.: Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines. European Journal of Medicinal Chemistry 246, 114990 (2022)

Krasavin, M.; Bubyrev, A.; Kazantsev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Dar'in, D.; Hartmann, M.; Brunev, A.: Replacing the phthalimide core in thalidomide with benzotriazole. Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), pp. 527 - 530 (2022)

Stahlecker, J.; Klett, T.; Schwer, M.; Jaag, S.; Dammann, M.; Ernst, L.; Braun, M.; Zimmermann, M.; Kramer, M.; Lämmerhofer, M. et al.; Stehle, T.; Coles, M.; Boeckler, F.: Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C. RSC Medicinal Chemistry 13 (12), pp. 1575 - 1586 (2022)

Barkhatova, D.; Zhukovsky, D.; Heim, C.; Maiwald, S.; Hartmann, M.; Krasavin, M.: Synthesis of novel glutarimide derivatives via the Ugi multicomponent reaction: affinity towards the E3 ubiquitin ligase substrate receptor Cereblon. Mendeleev Communications 32 (6), pp. 747 - 749 (2022)

Dammann, M.; Stahlecker, J.; Zimmermann, M.; Klett, T.; Rotzinger, K.; Kramer, M.; Coles, M.; Stehle, T.; Boeckler, F.: Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes. Journal of Medicinal Chemistry 65 (21), pp. 14539 - 14552 (2022)

Eenink, B.; Kaminski, T.; Bornberg-Bauer, E.; Jose, J.; Hollfelder, F.; van Loo, B.: Vector redesign and in-droplet cell-growth improves enrichment and recovery in live Escherichia coli. Microbial Biotechnology 15 (11), pp. 2845 - 2853 (2022)

Escobedo, A.; Piccirillo, J.; Aranda, J.; Diercks, T.; Mateos, B.; Garcia-Cabau, C.; Sánchez-Navarro, M.; Topal, B.; Biesaga, M.; Staby, L. et al.; Kragelund, B.; García, J.; Millet, O.; Orozco, M.; Coles, M.; Crehuet, R.; Salvatella, X.: A glutamine-based single α-helix scaffold to target globular proteins. Nature Communications 13 (1), 7073 (2022)

Berger, J.; Legendre, F.; Zelosko, K.-M.; Harrison, M.; Grandcolas, P.; Bornberg-Bauer, E.; Fouks, B.: Eusocial Transition in Blattodea: Transposable Elements and Shifts of Gene Expression. Genes 13 (11), 1948 (2022)

Singh, J.; Elhabashy, H.; Muthukottiappan, P.; Stepath, M.; Eisenacher, M.; Kohlbacher, O.; Gieselmann, V.; Winter, D.: Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo. Nature Communications 13 (1), 6212 (2022)

Srivastava, A.; Selim, K.: Inheritable nanotubes boost bioimaging and photovoltaics in cyanobacteria. Nature Nanotechnology 17 (10), pp. 1046 - 1047 (2022)

Iskhakova, Z.; Zhuravleva, D.; Heim, C.; Hartmann, M.; Laykov , A.; Forchhammer, K.; Kayumov, A.: PotN represents a novel energy-state sensing PII subfamily, occurring in firmicutes. The FEBS Journal 289 (17), pp. 5305 - 5321 (2022)

Seth, A.; Landau, M.; Shevchenko, A.; Schultz, A.; Elsabbagh, S.; Schultz, J.: Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity. Cellular Signalling 97, 110396 (2022)

Eicholt, L.; Aubel, M.; Berk, K.; Bornberg-Bauer, E.; Lange, A.: Heterologous expression of naturally evolved putative de novo proteins with chaperones. Protein Science 31 (8), e4371 (2022)

von Kügelgen, A.; van Dorst, S.; Alva, V.; Bharat, T.: A multidomain connector links the outer membrane and cell wall in phylogenetically deep-branching bacteria. Proceedings of the National Academy of Sciences of the United States of America 119 (33), e2203156119 (2022)

Braun, V.; Hartmann, M.; Hantke, K.: Transcription regulation of iron carrier transport genes by ECF sigma factors through signaling from the cell surface into the cytoplasm. FEMS Microbiology Reviews 46 (4), fuac010 (2022)

Braun, V.: Transkriptionskontrolle über bakterielle Membranen. Biospektrum 28 (4), pp. 374 - 376 (2022)

Pereira, J.; Lupas, A.: New β-Propellers Are Continuously Amplified From Single Blades in all Major Lineages of the β-Propeller Superfamily. Frontiers in Molecular Biosciences 9, 895496 (2022)

Skokowa, J.; Hernandez Alvarez, B.; Coles, M.; Ritter, M.; Nasri, M.; Haaf, J.; Aghaallaei, N.; Xu, Y.; Mir, P.; Krahl, A.-C. et al.; Rogers, K.; Maksymenko, K.; Bajoghli, B.; Welte, K.; Lupas, A.; Müller, P.; ElGamacy, M.: A topological refactoring design strategy yields highly stable granulopoietic proteins. Nature Communications 13 (1), 2948 (2022)