Many proteins share detectable similarities in sequence and structure. Sequence-based comparison of modern proteins shows that they fall into only about ten thousand domain families
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Using a variety of biochemistry, biophysics and microbiology techniques, we focus on prokaryotic model systems to better understand these intricate processes.
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The primary goal of structural biology is a mechanistic understanding of biological macromolecules and of biological processes so that they can be described in the language of physics and chemistry.
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