Publikationen
Transmembran-Signaltransduktion
Zeitschriftenartikel (32)
1.
Zeitschriftenartikel
Epub ahead (2024)
Covalent Fragments Acting as Tyrosine Mimics for Mutant p53-Y220C Rescue by Nucleophilic Aromatic Substitution. ACS Pharmacology & Translational Science 2.
Zeitschriftenartikel
13 (12), S. 1575 - 1586 (2022)
Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C. RSC Medicinal Chemistry 3.
Zeitschriftenartikel
65 (21), S. 14539 - 14552 (2022)
Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes. Journal of Medicinal Chemistry 4.
Zeitschriftenartikel
13 (1), 7073 (2022)
A glutamine-based single α-helix scaffold to target globular proteins. Nature Communications 5.
Zeitschriftenartikel
13 (1), 2948 (2022)
A topological refactoring design strategy yields highly stable granulopoietic proteins. Nature Communications 6.
Zeitschriftenartikel
478 (10), S. 1885 - 1890 (2021)
The breakthrough in protein structure prediction. Biochemical Journal 7.
Zeitschriftenartikel
18 (12), e3000919 (2020)
Design of novel granulopoietic proteins by topological rescaffolding. PLoS Biology 8.
Zeitschriftenartikel
58 (48), S. 4790 - 4793 (2019)
Reconstructing the Remote Origins of a Fold Singleton from a Flavodoxin-Like Ancestor. Biochemistry 9.
Zeitschriftenartikel
27 (5), S. 853 - 865 (2019)
Mapping Local Conformational Landscapes of Proteins in Solution. Structure 10.
Zeitschriftenartikel
27 (3), S. 464 - 475 (2019)
Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles. Structure 11.
Zeitschriftenartikel
204 (3), S. 380 - 387 (2018)
Asymmetric protein design from conserved supersecondary structures. Journal of Structural Biology 12.
Zeitschriftenartikel
7 (9), S. 2226 - 2235 (2018)
An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture. ACS Synthetic Biology 13.
Zeitschriftenartikel
5 (26), e16761 (2016)
Origin of a folded repeat protein from an intrinsically disordered ancestor. eLife 14.
Zeitschriftenartikel
6, 26707 (2016)
Solution structure and binding specificity of the p63 DNA binding domain. Scientific Reports 15.
Zeitschriftenartikel
18 (1), S. 118 - 132 (2016)
Distinct mechanisms contribute to immunity in the lantibiotic NAI-107 producer strain Microbispora ATCC PTA-5024. Environmental Microbiology 16.
Zeitschriftenartikel
427 (20), S. 3327 - 3339 (2015)
STAC: A New Domain Associated with Transmembrane Solute Transport and Two-Component Signal Transduction Systems. Journal of Molecular Biology 17.
Zeitschriftenartikel
10 (5), e0128342 (2015)
Structural dynamics of the cereblon ligand binding domain. PLoS One 18.
Zeitschriftenartikel
427 (4), S. 910 - 923 (2015)
Structure and evolution of N-domains in AAA metalloproteases. Journal of Molecular Biology 19.
Zeitschriftenartikel
95 (1), S. 80 - 100 (2015)
The Intimin periplasmic domain mediates dimerisation and binding to peptidoglycan. Molecular Microbiology 20.
Zeitschriftenartikel
188 (3), S. 225 - 232 (2014)
Thalidomide mimics uridine binding to an aromatic cage in cereblon. Journal of Structural Biology