Publikationen

Chen, Y.; Khazina, E.; Izaurralde, E.; Weichenrieder, O.: Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex. Nucleic Acids Research (London) 49 (11), S. 6489 - 6510 (2021)

Keskeny, C.; Raisch, T.; Sgromo, A.; Igreja, C.; Bhandari, D.; Weichenrieder, O.; Izaurralde, E.: A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex. Genes and Development 33 (3-4), S. 236 - 252 (2019)

Raisch, T.; Sandmeir, F.; Weichenrieder, O.; Valkov, E.; Izaurralde, E.: Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex. Journal of Structural Biology 204 (3), S. 388 - 395 (2018)

Weichenrieder, O.: Elisa Izaurralde (1959-2018). Cell 174 (1), S. P5 - P6 (2018)

Khazina, E.; Weichenrieder, O.: Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p. eLife 7, e34960 (2018)

Sgromo, A.; Raisch, T.; Backhaus, C.; Keskeny, C.; Alva, V.; Weichenrieder, O.; Izaurralde, E.: Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets. RNA-A Publication of the RNA Society 24 (3), S. 381 - 395 (2018)

MacLennan, M.; García-Cañadas, M.; Reichmann, J.; Khazina, E.; Wagner, G.; Playfoot, C.; Salvador-Palomeque, C.; Mann, A.; Peressini, P.; Sanchez, L. et al.; Dobie, K.; Read, C.; Hung, C.-C.; Eskeland, R.; Meehan, R.; Weichenrieder, O.; Luis Garcia-Perez, J.; Adams, I.: Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. eLife 6, e26152 (2017)

Sgromo, A.; Raisch, T.; Bawankar, P.; Bhandari, D.; Chen, Y.; Kuzuoğlu-Öztürk, D.; Weichenrieder, O.; Izaurralde, E.: A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin. Nature Communications 8, 14307 (2017)

Valkov, E.; Jonas, S.; Weichenrieder, O.: Mille viae in eukaryotic mRNA decapping. Current Opinion in Structural Biology 47, S. 40 - 51 (2017)

Grüner, S.; Peter, D.; Weber, R.; Wohlbold, L.; Chung, M.-Y.; Weichenrieder, O.; Valkov, E.; Igreja, C.; Izaurralde, E.: The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Molecular Cell 64 (3), S. 467 - 479 (2016)

Valkov, E.; Muthukumar, S.; Chang, C.-T.; Jonas, S.; Weichenrieder, O.; Izaurralde, E.: Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nature Structural and Molecular Biology 23 (6), S. 574 - 579 (2016)

Raisch, T.; Bhandari, D.; Sabath, K.; Helms, S.; Valkov, E.; Weichenrieder, O.; Izaurralde, E.: Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos. EMBO Journal 35 (9), S. 974 - 990 (2016)

Peter, D.; Weber, R.; Köne, C.; Chung, M.-Y.; Ebertsch, L.; Truffault, V.; Weichenrieder, O.; Igreja, C.; Izaurralde, E.: Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation. Genes and Development 29 (17), S. 1835 - 1849 (2015)

Peter, D.; Igreja, C.; Weber, R.; Wohlbold, L.; Weiler, C.; Ebertsch, L.; Weichenrieder, O.; Izaurralde, E.: Molecular architecture of 4E-BP translational inhibitors bound to eIF4E. Molecular Cell 57 (6), S. 1074 - 1087 (2015)

Jonas, S.; Christie, M.; Peter, D.; Bhandari, D.; Loh, B.; Huntzinger, E.; Weichenrieder, O.; Izaurralde, E.: An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay. Nature Structural and Molecular Biology 21 (7), S. 599 - 608 (2014)

Chen, Y.; Boland, A.; Kuzuoğlu-Öztürk, D.; Bawankar, P.; Loh, B.; Chang, C.-T.; Weichenrieder, O.; Izaurralde, E.: A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing. Molecular Cell 54 (5), S. 737 - 750 (2014)

Weichenrieder, O.: RNA binding by Hfq and ring-forming (L)Sm proteins: a trade-off between optimal sequence readout and RNA backbone conformation. RNA Biology 11 (5), S. 537 - 549 (2014)

Bhandari, D.; Raisch, T.; Weichenrieder, O.; Jonas, S.; Izaurralde, E.: Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression. Genes and Development 28 (8), S. 888 - 901 (2014)

Schneider, A.; Schmidt, S.; Jonas, S.; Vollmer, B.; Khazina, E.; Weichenrieder, O.: Structure and properties of the esterase from non-LTR retrotransposons suggest a role for lipids in retrotransposition. Nucleic Acids Research (London) 41 (22), S. 10563 - 10572 (2013)

Boland, A.; Chen, Y.; Raisch, T.; Jonas, S.; Kuzuoğlu-Öztürk, D.; Wohlbold, L.; Weichenrieder, O.; Izaurralde, E.: Structure and assembly of the NOT module of the human CCR4-NOT complex. Nature Structural and Molecular Biology 20 (11), S. 1289 - 1297 (2013)