Publikationen

Baldwin, E.; van Eeuwen, T.; Hoyos, D.; Zalevsky, A.; Tchesnokov, E.; Sánchez, R.; Miller, B.; Di Stefano, L.; Ruiz, F.; Hancock, M. et al.; Işik, E.; Mendez-Dorantes, C.; Walpole, T.; Nichols, C.; Wan, P.; Riento, K.; Halls-Kass, R.; Augustin, M.; Lammens, A.; Jestel, A.; Upla, P.; Xibinaku, K.; Congreve, S.; Hennink, M.; Rogala, K.; Schneider, A.; Fairman, J.; Christensen, S.; Desrosiers, B.; Bisacchi, G.; Saunders, O.; Hafeez, N.; Miao, W.; Kapeller, R.; Zaller, D.; Sali, A.; Weichenrieder, O.; Burns, K.; Götte, M.; Rout, M.; Arnold, E.; Greenbaum, B.; Romero, D.; LaCava, J.; Taylor, M.: Structures, functions, and adaptations of the human LINE-1 ORF2 protein. Nature 626 (7997), S. 194 - 206 (2024)

Chen, Y.; Khazina, E.; Izaurralde, E.; Weichenrieder, O.: Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex. Nucleic Acids Research (London) 49 (11), S. 6489 - 6510 (2021)

Weichenrieder, O.: Cellular Traffic Jam and Disease Due to Mutations in SRP54. Structure 29 (1), S. 3 - 5 (2021)

Keskeny, C.; Raisch, T.; Sgromo, A.; Igreja, C.; Bhandari, D.; Weichenrieder, O.; Izaurralde, E.: A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex. Genes and Development 33 (3-4), S. 236 - 252 (2019)

Raisch, T.; Sandmeir, F.; Weichenrieder, O.; Valkov, E.; Izaurralde, E.: Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex. Journal of Structural Biology 204 (3), S. 388 - 395 (2018)

Khazina, E.; Weichenrieder, O.: Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p. eLife 7, e34960 (2018)

Sgromo, A.; Raisch, T.; Backhaus, C.; Keskeny, C.; Alva, V.; Weichenrieder, O.; Izaurralde, E.: Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets. RNA-A Publication of the RNA Society 24 (3), S. 381 - 395 (2018)

MacLennan, M.; García-Cañadas, M.; Reichmann, J.; Khazina, E.; Wagner, G.; Playfoot, C.; Salvador-Palomeque, C.; Mann, A.; Peressini, P.; Sanchez, L. et al.; Dobie, K.; Read, C.; Hung, C.-C.; Eskeland, R.; Meehan, R.; Weichenrieder, O.; Luis Garcia-Perez, J.; Adams, I.: Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. eLife 6, e26152 (2017)

Sgromo, A.; Raisch, T.; Bawankar, P.; Bhandari, D.; Chen, Y.; Kuzuoğlu-Öztürk, D.; Weichenrieder, O.; Izaurralde, E.: A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin. Nature Communications 8, 14307 (2017)

Valkov, E.; Jonas, S.; Weichenrieder, O.: Mille viae in eukaryotic mRNA decapping. Current Opinion in Structural Biology 47, S. 40 - 51 (2017)

Grüner, S.; Peter, D.; Weber, R.; Wohlbold, L.; Chung, M.-Y.; Weichenrieder, O.; Valkov, E.; Igreja, C.; Izaurralde, E.: The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Molecular Cell 64 (3), S. 467 - 479 (2016)

Valkov, E.; Muthukumar, S.; Chang, C.-T.; Jonas, S.; Weichenrieder, O.; Izaurralde, E.: Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nature Structural and Molecular Biology 23 (6), S. 574 - 579 (2016)

Raisch, T.; Bhandari, D.; Sabath, K.; Helms, S.; Valkov, E.; Weichenrieder, O.; Izaurralde, E.: Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos. EMBO Journal 35 (9), S. 974 - 990 (2016)

Ahl, V.; Keller, H.; Schmidt, S.; Weichenrieder, O.: Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling Conformation. Molecular Cell 60 (5), S. 715 - 727 (2015)

Peter, D.; Weber, R.; Köne, C.; Chung, M.-Y.; Ebertsch, L.; Truffault, V.; Weichenrieder, O.; Igreja, C.; Izaurralde, E.: Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation. Genes and Development 29 (17), S. 1835 - 1849 (2015)

Peter, D.; Igreja, C.; Weber, R.; Wohlbold, L.; Weiler, C.; Ebertsch, L.; Weichenrieder, O.; Izaurralde, E.: Molecular architecture of 4E-BP translational inhibitors bound to eIF4E. Molecular Cell 57 (6), S. 1074 - 1087 (2015)

Weinert, T.; Olieric, V.; Waltersperger, S.; Panepucci, E.; Chen, L.; Zhang, H.; Zhou, D.; Rose, J.; Ebihara, A.; Kuramitsu, S. et al.; Li, D.; Howe, N.; Schnapp, G.; Pautsch, A.; Bargsten, K.; Prota, A.; Surana, P.; Kottur, J.; Jair, D.; Basilico, F.; Cecatiello, V.; Pasqualato, S.; Boland, A.; Weichenrieder, O.; Wang, B.-C.; Steinmetz, M.; Caffrey, M.; Wang, M.: Fast native-SAD phasing for routine macromolecular structure determination. Nature Methods 12 (2), S. 131 - 133 (2015)

Jonas, S.; Christie, M.; Peter, D.; Bhandari, D.; Loh, B.; Huntzinger, E.; Weichenrieder, O.; Izaurralde, E.: An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay. Nature Structural and Molecular Biology 21 (7), S. 599 - 608 (2014)

Chen, Y.; Boland, A.; Kuzuoğlu-Öztürk, D.; Bawankar, P.; Loh, B.; Chang, C.-T.; Weichenrieder, O.; Izaurralde, E.: A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing. Molecular Cell 54 (5), S. 737 - 750 (2014)

Weichenrieder, O.: RNA binding by Hfq and ring-forming (L)Sm proteins: a trade-off between optimal sequence readout and RNA backbone conformation. RNA Biology 11 (5), S. 537 - 549 (2014)