Publications
^{_{Protein Bioinformatics}}

Zibat, A.; Zhang, X.; Dickmanns, A.; Stegmann, K.; Dobbelstein, A.; Alachram, H.; Soliwoda, R.; Salinas, G.; Görlich, D.; Kschischo, M. et al.; Wollnik, B.; Dobbelstein, M.: N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody. iScience 26 (10), 107786 (2023)

Kaminski, K.; Ludwiczak, J.; Pawlicki, K.; Alva, V.; Dunin-Horkawicz, S.: pLM-BLAST: distant homology detection based on direct comparison of sequence representations from protein language models. Bioinformatics Epub ahead, btad579 (2023)

Böhning, J.; Dobbelstein, A.; Sulkowski, N.; Eilers, K.; von Kügelgen, A.; Tarafder, A.; Peak-Chew, S.-Y.; Skehel, M.; Alva, V.; Filloux, A. et al.; Bharat, T.: Architecture of the biofilm-associated archaic Chaperone-Usher pilus CupE from Pseudomonas aeruginosa. PLoS Pathogens 19 (4), e1011177 (2023)

von Kügelgen, A.; van Dorst, S.; Yamashita, K.; Sexton, D.; Tocheva, E.; Murshudov, G.; Alva, V.; Bharat, T.: Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans. Proceedings of the National Academy of Sciences of the United States of America 120 (16), e2215808120 (2023)

von Kügelgen, A.; van Dorst, S.; Alva, V.; Bharat, T.: A multidomain connector links the outer membrane and cell wall in phylogenetically deep-branching bacteria. Proceedings of the National Academy of Sciences of the United States of America 119 (33), e2203156119 (2022)

Elhabashy, H.; Merino, F.; Alva, V.; Kohlbacher, O.; Lupas, A.: Exploring protein-protein interactions at the proteome level. Structure 30 (4), pp. 462 - 475 (2022)

von Kügelgen, A.; Alva, V.; Bharat, T.: Complete atomic structure of a native archaeal cell surface. Cell Reports 37 (8), 110052 (2021)

Pereira, J.; Alva, V.: How do I get the most out of my protein sequence using bioinformatics tools? Acta Crystallographica Section D: Structural Biology 77 (9), pp. 1116 - 1126 (2021)

Fuchs, A.; Alva, V.; Lupas, A.: An astonishing wealth of new proteasome homologs. Bioinformatics 37 (24), pp. 4694 - 4703 (2021)

Bharat, T.; von Kügelgen, A.; Alva, V.: Molecular Logic of Prokaryotic Surface Layer Structures. Trends in Microbiology 29 (5), pp. 405 - 415 (2021)

Lupas, A.; Pereira, J.; Alva, V.; Merino, F.; Coles, M.; Hartmann, M.: The breakthrough in protein structure prediction. Biochemical Journal 478 (10), pp. 1885 - 1890 (2021)

Selim, K.; Tremiño, L.; Marco-Marín, C.; Alva, V.; Espinosa, J.; Contreras, A.; Hartmann, M.; Forchhammer, K.; Rubio, V.: Functional and structural characterization of PII-like protein CutA does not support involvement in heavy metal tolerance and hints at a small-molecule carrying/signaling role. The FEBS Journal 288 (4), pp. 1142 - 1162 (2021)

Gabler, F.; Nam, S.-Z.; Till, S.; Mirdita, M.; Steinegger, M.; Söding, J.; Lupas, A.; Alva, V.: Protein sequence analysis using the MPI Bioinformatics Toolkit. Current Protocols in Bioinformatics 72 (1), e108 (2020)

Seefelder, M.; Alva, V.; Huang, B.; Engler, T.; Baumeister, W.; Guo, Q.; Fernandez-Busnadiego, R.; Lupas, A.; Kochanek, S.: The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin. BMC Evolutionary Biology 20 (1), 162 (2020)

Narunsky, A.; Kessel, A.; Solan, R.; Alva, V.; Kolodny, R.; Ben-Tal, N.: On the evolution of protein-adenine binding. Proceedings of the National Academy of Sciences of the United States of America 117 (9), pp. 4701 - 4709 (2020)

Lauer, J.; Segeletz, S.; Cezanne, A.; Guaitoli, G.; Raimondi, F.; Gentzel, M.; Alva, V.; Habeck, M.; Kalaidzidis, Y.; Ueffing, M. et al.; Lupas, A.; Gloeckner, C.; Zerial, M.: Auto-regulation of Rab5 GEF activity in Rabex5 by allosteric structural changes, catalytic core dynamics and ubiquitin binding. eLife 8, e46302 (2019)

Afanasieva, E.; Chaudhuri, I.; Martin, J.; Hertle, E.; Ursinus, A.; Alva, V.; Hartmann, M.; Lupas, A.: Structural diversity of oligomeric β-propellers with different numbers of identical blades. eLife 8, e49853 (2019)

Brault, M.; Petit, J.; Immel, F.; Nicolas, W.; Glavier, M.; Brocard, L.; Gaston, A.; Fouché, M.; Hawkins, T.; Crowet, J.-M. et al.; Grison, M.; Germain, V.; Rocher, M.; Kraner, M.; Alva, V.; Claverol, S.; Paterlini, A.; Helariutta, Y.; Deleu, M.; Lins, L.; Tilsner, J.; Bayer, E.: Multiple C2 domains and transmembrane region proteins (MCTPs) tether membranes at plasmodesmata. EMBO Reports 20 (8), e47182 (2019)

Ludwiczak, J.; Winski, A.; Szczepaniak , A.; Alva, V.; Dunin-Horkawicz, S.: DeepCoil-a fast and accurate prediction of coiled-coil domains in protein sequences. Bioinformatics 35 (16), pp. 2790 - 2795 (2019)

Alva, V.; Lupas, A.: Histones Predate the Split Between Bacteria and Archaea. Bioinformatics 35 (14), pp. 2349 - 2353 (2019)