Publications of E Valkov

Shah, K.; He, S.; Turner, D.; Corbo, J.; Rebbani, K.; Dominguez, D.; Bateman, D.; Cheloufi, S.; Igreja, C.; Valkov, E. et al.; Murn, J.: Regulation by the RNA-binding protein Unkempt at its effector interface. Nature Communications 15 (1), 3159 (2024)

Weber, R.; Kleemann, L.; Hirschberg, I.; Chung, M.-Y.; Valkov, E.; Igreja, C.: DAP5 enables main ORF translation on mRNAs with structured and uORF-containing 5' leaders. Nature Communications 13 (1), 7510 (2022)

Enwerem, I.; Elrod, N.; Chang, C.-T.; Lin, A.; Ji, P.; Bohn, J.; Levdansky, Y.; Wagner, E.; Valkov, E.; Goldstrohm, A.: Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome. RNA 27 (4), pp. 44 - 464 (2021)

Weber, R.; Chung, M.-Y.; Keskeny, C.; Zinnall, U.; Landthaler, M.; Valkov, E.; Izaurralde, E.; Igreja, C.: 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. Cell Reports 33 (2), 108262 (2020)

Arvola, R.; Chang, C.-T.; Buytendorp, J.; Levdansky, Y.; Valkov, E.; Freddolino, P.; Goldstrohm, A.: Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs. Nucleic Acids Research (London) 48 (4), pp. 1843 - 1871 (2020)

Peter, D.; Ruscica, V.; Bawankar, P.; Weber, R.; Helms, S.; Valkov, E.; Igreja, C.; Izaurralde, E.: Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes and Development 33 (19-20), pp. 1355 - 1360 (2019)

Chang, C.-T.; Muthukumar, S.; Weber, R.; Levdansky, Y.; Chen, Y.; Bhandari, D.; Igreja, C.; Wohlbold, L.; Valkov, E.; Izaurralde, E.: A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay. Nucleic Acids Research (London) 47 (17), pp. 9282 - 9295 (2019)

Raisch, T.; Chang, C.-T.; Levdansky, Y.; Muthukumar, S.; Raunser, S.; Valkov, E.: Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation. Nature Communications 10, 3173 (2019)

Raisch, T.; Sandmeir, F.; Weichenrieder, O.; Valkov, E.; Izaurralde, E.: Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex. Journal of Structural Biology 204 (3), pp. 388 - 395 (2018)

Grüner, S.; Weber, R.; Peter, D.; Chung, M.-Y.; Igreja, C.; Valkov, E.; Izaurralde, E.: Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast. Nucleic Acids Research (London) 46 (13), pp. 6893 - 6908 (2018)

van Loo, B.; Schober, M.; Valkov, E.; Heberlein, M.; Bornberg-Bauer, E.; Faber, K.; Hyvönen, M.; Hollfelder, F.: Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester. Journal of Molecular Biology 430 (7), pp. 1004 - 1023 (2018)

Peter, D.; Weber, R.; Sandmeir, F.; Wohlbold, L.; Helms, S.; Bawankar, P.; Valkov, E.; Igreja, C.; Izaurralde, E.: GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes and Development 31 (11), pp. 1147 - 1161 (2017)

Valkov, E.; Jonas, S.; Weichenrieder, O.: Mille viae in eukaryotic mRNA decapping. Current Opinion in Structural Biology 47, pp. 40 - 51 (2017)

Grüner, S.; Peter, D.; Weber, R.; Wohlbold, L.; Chung, M.-Y.; Weichenrieder, O.; Valkov, E.; Igreja, C.; Izaurralde, E.: The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Molecular Cell 64 (3), pp. 467 - 479 (2016)

Valkov, E.; Muthukumar, S.; Chang, C.-T.; Jonas, S.; Weichenrieder, O.; Izaurralde, E.: Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nature Structural and Molecular Biology 23 (6), pp. 574 - 579 (2016)

Raisch, T.; Bhandari, D.; Sabath, K.; Helms, S.; Valkov, E.; Weichenrieder, O.; Izaurralde, E.: Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos. EMBO Journal 35 (9), pp. 974 - 990 (2016)

Grüner, S.; Chung, M.; Valkov, E.; Igreja, C.; Izaurralde, E.: Crystal structures of fungal eIF4G and 4E-BPs bound to eIF4E provide insight into the regulation of translation initiation. In The FEBS Journal, 284 (Supplement 1), ShT.4.2-001, p. 41. 42nd FEBS Congress: From Molecules to Cells and Back, Jerusalem, Israel, September 10, 2017 - September 14, 2017. Wiley-Blackwell (2017)