Publications of R Weber

Weber, R.; Wohlbold, L.; Chang, C.-T.: Human DDX6 regulates translation and decay of inefficiently translated mRNAs. eLife Epub ahead (2024)

Weber, R.; Kleemann, L.; Hirschberg, I.; Chung, M.-Y.; Valkov, E.; Igreja, C.: DAP5 enables main ORF translation on mRNAs with structured and uORF-containing 5' leaders. Nature Communications 13 (1), 7510 (2022)

Weber, R.; Chung, M.-Y.; Keskeny, C.; Zinnall, U.; Landthaler, M.; Valkov, E.; Izaurralde, E.; Igreja, C.: 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. Cell Reports 33 (2), 108262 (2020)

Räsch, F.; Weber, R.; Izaurralde, E.; Igreja, C.: 4E-T-bound mRNAs are stored in a silenced and deadenylated form. Genes and Development 34 (11-12), pp. 847 - 860 (2020)

Peter, D.; Ruscica, V.; Bawankar, P.; Weber, R.; Helms, S.; Valkov, E.; Igreja, C.; Izaurralde, E.: Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes and Development 33 (19-20), pp. 1355 - 1360 (2019)

Chang, C.-T.; Muthukumar, S.; Weber, R.; Levdansky, Y.; Chen, Y.; Bhandari, D.; Igreja, C.; Wohlbold, L.; Valkov, E.; Izaurralde, E.: A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay. Nucleic Acids Research (London) 47 (17), pp. 9282 - 9295 (2019)

Hanet, A.; Räsch, F.; Weber, R.; Ruscica, V.; Fauser, M.; Raisch, T.; Kuzuoglu-Öztürk, D.; Chang, C.-T.; Bhandari, D.; Igreja, C. et al.; Wohlbold, L.: HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs. Life science alliance 2 (5), e201900405 (2019)

Grüner, S.; Weber, R.; Peter, D.; Chung, M.-Y.; Igreja, C.; Valkov, E.; Izaurralde, E.: Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast. Nucleic Acids Research (London) 46 (13), pp. 6893 - 6908 (2018)

Peter, D.; Weber, R.; Sandmeir, F.; Wohlbold, L.; Helms, S.; Bawankar, P.; Valkov, E.; Igreja, C.; Izaurralde, E.: GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes and Development 31 (11), pp. 1147 - 1161 (2017)

Grüner, S.; Peter, D.; Weber, R.; Wohlbold, L.; Chung, M.-Y.; Weichenrieder, O.; Valkov, E.; Igreja, C.; Izaurralde, E.: The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Molecular Cell 64 (3), pp. 467 - 479 (2016)

Peter, D.; Weber, R.; Köne, C.; Chung, M.-Y.; Ebertsch, L.; Truffault, V.; Weichenrieder, O.; Igreja, C.; Izaurralde, E.: Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation. Genes and Development 29 (17), pp. 1835 - 1849 (2015)

Peter, D.; Igreja, C.; Weber, R.; Wohlbold, L.; Weiler, C.; Ebertsch, L.; Weichenrieder, O.; Izaurralde, E.: Molecular architecture of 4E-BP translational inhibitors bound to eIF4E. Molecular Cell 57 (6), pp. 1074 - 1087 (2015)

Peter, D.; Igreja, C.; Weber, R.; Wohlbold, L.; Weiler, C.; Ebertsch, L.; Weichenrieder, O.; Izaurralde, E.: Molecular architecture of 4E-BP translational inhibitors bound to eIF4E. In Twentieth Annual Meeting of the RNA Society, 92, p. 116. Twentieth Annual Meeting of the RNA Society, Madison, WI, USA, May 26, 2015 - May 31, 2015. (2015)

Weber, R.: Translational control by eukaryotic initiation factor (eIF) 4E and 4G homologous proteins. Dissertation, Eberhard-Karls-Universität, Tübingen, Germany (2020)