Publications
_{Microbiome Engineering}

Marsh, J.; Kirk, C.; Ley, R.: Toward Microbiome Engineering: Expanding the Repertoire of Genetically Tractable Members of the Human Gut Microbiome. Annual Review of Microbiology 77, pp. 427 - 449 (2023)

Marsh, J.; Ley, R.: Microbiome engineering: Taming the untractable. Cell 185 (3), pp. 416 - 418 (2022)

Hayward, R.; Marsh, J.; Humphrys, M.; Huston, W.; Myers, G.: Chromatin accessibility dynamics of Chlamydia-infected epithelial cells. Epigenetics & Chromatin 13, 45 (2020)

Hayward, R.; Marsh, J.; Humphrys, M.; Huston, W.; Myers, G.: Early Transcriptional Landscapes of Chlamydia trachomatis-Infected Epithelial Cells at Single Cell Resolution. Frontiers in Cellular and Infection Microbiology 9, 392 (2019)

Agbowuro, A.; Hwang, J.; Peel, E.; Mazraani, R.; Springwald, A.; Marsh, J.; McCaughey, L.; Gamble, A.; Huston, W.; Tyndall, J.: Structure-activity analysis of peptidic Chlamydia HtrA inhibitors. Bioorganic & Medicinal Chemistry 27 (18), pp. 4185 - 4199 (2019)

Marsh, J.; Hayward, R.; Shetty, A.; Mahurkar, A.; Humphrys, M.; Myers, G.: Bioinformatic analysis of bacteria and host cell dual RNA-sequencing experiments. Briefings in Bioinformatics 19 (6), pp. 1115 - 1129 (2018)

Marsh, J.; Djoko, A.; McEwan, A.; Huston, W.: Copper(II)-bis(thiosemicarbazonato) complexes as anti-chlamydial agents. Pathogens and Disease 75 (7), ftx084 (2017)

Marsh, J.; Humphrys, M.; Myers, G.: A Laboratory Methodology for Dual RNA-Sequencing of Bacteria and their Host Cells In Vitro. Frontiers in Microbiology 8, 1830 (2017)

Marsh, J.; Ong, V.; Lott, W.; Timms, P.; Tyndall, J.; Huston, W.: CtHtrA: the lynchpin of the chlamydial surface and a promising therapeutic target. Future Microbiology 12 (9), pp. 817 - 829 (2017)

Marsh, J.; Wee, B.; Tyndall, J.; Lott, W.; Bastidas, R.; Caldwell, H.; Valdivia, R.; Kari, L.; Huston, W.: A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production. BMC Microbiology 15, 194 (2015)

Marsh, J.; Lott, W.; Tyndall, J.; Huston, W.: Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand β5. Cellular & Molecular Biology Letters 18 (4), pp. 522 - 537 (2013)

Ong, V.; Marsh, J.; Lawrence, A.; Allan, J.; Timms, P.; Huston, W.: The protease inhibitor JO146 demonstrates a critical role for CtHtrA for Chlamydia trachomatis reversion from penicillin persistence. Frontiers in Cellular and Infection Microbiology 3, 100 (2013)

Marsh, J.; Kollipara, A.; Timms, P.; Polkinghorne, A.: Novel molecular markers of Chlamydia pecorum genetic diversity in the koala (Phascolarctos cinereus). BMC Microbiology 11, 77 (2011)

Marsh, J.; Hayward, R.; Shetty, A.; Mahurkar, A.; Humphrys, M.; Myers, G.: Dual RNA-Seq of Chlamydia and Host Cells. In: Methods in Molecular Biology, Vol. 2042. Springer, US (2019)

Marsh, J.; Gloeckl, S.; Tyndall, J.; Huston, W.: The role of HtrA as a chaperone and protease in bacterial pathogenesis. In: Bacterial pathogens: Virulence mechanisms, diagnosis and management, pp. 117 - 164 (Eds. Blanc, M.; Boulanger, A.). Nova Science Publishers, Hauppauge, NY, USA (2011)

Bryson, A.; Chatterjee, M.; Holdermann, I.; Kirk, C.; Kisker, J.; Simic, I.; Ley, R.; Marsh, J.: Human Gut Microbiome Engineering: Unlocking the Genetic Vault. In SeaWheat COST Action Workshop: Advances in Biome Research of Ulva, p. 32. SeaWheat COST Action Workshop: Advances in Biome Research of Ulva, Faro, Portugal, March 18, 2025 - March 19, 2025. (2025)

Marsh, J.: Toward Microbiome Engineering: Expanding the Repertoire of Genetically Tractable Members of the Human Gut Microbiome. New Horizons in Precision Medical Imaging and Therapy Symposium, Tübingen, Germany (2022)

Chatterjee, M.; Holdermann, I.; Kirk, C.; Kisker, J.; Ley, R.; Marsh, J.: Updating microbial genetics tools for their application to the human gut microbiome. Annual Conference of the Microbiology Society 2024, Edinburgh, UK (2024)

Kirk, C.; Holdermann, I.; Bryson, A.; Chatterjee, M.; Kisker, J.; Ley, R.; Marsh, J.: Characterisation of the genetic determinants for R. hominis flagellin-host interactions. Annual Conference of the Microbiology Society 2024, Edinburgh, UK (2024)

Chatterjee, M.; Holdermann, I.; Kirk, C.; Kisker, J.; Ley, R.; Marsh, J.: Updating microbial genetics tools for their application to the human gut microbiome. 3rd International Conference Controlling Microbes to Fight Infections (CMFI 2023), Tübingen, Germany (2023)