Publications

Tritschler, F.; Braun, J.; Motz, C.; Igreja, C.; Haas, G.; Truffault, V.; Izaurralde, E.; Weichenrieder, O.: DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Proceedings of the National Academy of Sciences of the United States of America 106 (51), pp. 21591 - 21596 (2009)

Zekri, L.; Huntzinger, E.; Heimstädt, S.; Izaurralde, E.: The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release. Molecular and Cellular Biology (Washington, DC) 29 (23), pp. 6220 - 6231 (2009)

Hartmann, M.; Ridderbusch, O.; Zeth, K.; Albrecht, R.; Testa, O.; Woolfson, D.; Sauer, G.; Dunin-Horkawicz, S.; Lupas, A.; Hernandez Alvarez, B.: A coiled-coil motif that sequesters ions to the hydrophobic core. Proceedings of the National Academy of Sciences of the United States of America 106 (40), pp. 16950 - 16955 (2009)

Boehm, B.; Rosinger, S.; Sauer, G.; Manfras, B.; Schiekofer, S.; Kalbacher, H.; Burster, T.: Protease-resistant human GAD-derived altered peptide ligands decrease TNF-α and IL-17 production in peripheral blood cells from patients with type 1 diabetes mellitus. Molecular Immunology 46 (13), pp. 2576 - 2584 (2009)

Eulalio, A.; Tritschler, F.; Izaurralde, E.: The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing. RNA: A Publication of the RNA Society 15 (8), pp. 1433 - 1442 (2009)

Fernández-Santiago, R.; Hoenig, S.; Lichtner, P.; Sperfeld, A.-D.; Sharma, M.; Berg, D.; Weichenrieder, O.; Illig, T.; Eger, K.; Meyer, T. et al.; Anneser, J.; Münch, C.; Zierz, S.; Gasser, T.; Ludolph, A.: Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis. Journal of Neurology 256 (8), pp. 1337 - 1342 (2009)

Wittkopp, N.; Huntzinger, E.; Weiler, C.; Saulière, J.; Schmidt, S.; Sonawane, M.; Izaurralde, E.: Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Molecular and Cellular Biology (Washington, DC) 29 (13), pp. 3517 - 3528 (2009)

Eulalio, A.; Helms, S.; Fritzsch, C.; Fauser, M.; Izaurralde, E.: A C-terminal silencing domain in GW182 is essential for miRNA function. RNA: A Publication of the RNA Society 15 (6), pp. 1067 - 1077 (2009)

Hansen, K.; Lareau, L.; Blanchette, M.; Green, R.; Meng, Q.; Rehwinkel, J.; Gallusser, F.; Izaurralde, E.; Rio, D.; Dudoit, S.: Genome-Wide Identification of Alternative Splice Forms Down-Regulated by Nonsense-Mediated mRNA Decay in Drosophila. PLoS Genetics 6 (5), e1000525 (2009)

Izaurralde, E.: Freedom versus constraint in protein function. Nature Reviews Molecular Cell Biology 10 (6), p. 372 (2009)

Lazzaretti, D.; Tournier, I.; Izaurralde, E.: The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins. RNA: A Publication of the RNA Society 15 (6), pp. 1059 - 1066 (2009)

Eulalio, A.; Tritschler, F.; Büttner, R.; Weichenrieder, O.; Izaurralde, E.; Truffault, V.: The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Nucleic Acids Research (London) 37 (9), pp. 2974 - 2983 (2009)

Schmid, A.; Neumayer, W.; Trülzsch, K.; Israel, L.; Imhof, A.; Roessle, M.; Sauer, G.; Richter, S.; Lauw, S.; Eylert, E. et al.; Eisenreich, W.; Heesemann, J.; Wilharm, G.: Cross-talk between type three secretion system and metabolism in Yersinia. The Journal of Biological Chemistry 284 (18), pp. 12165 - 12177 (2009)

Tritschler, F.; Braun, J.; Eulalio, A.; Truffault, V.; Izaurralde, E.; Weichenrieder, O.: Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Molecular Cell 33 (5), pp. 661 - 668 (2009)

Eulalio, A.; Huntzinger, E.; Nishihara, T.; Rehwinkel, J.; Fauser, M.; Izaurralde, E.: Deadenylation is a widespread effect of miRNA regulation. RNA: A Publication of the RNA Society 15 (1), pp. 21 - 32 (2009)

Khazina, E.; Weichenrieder, O.: Non-LTR retrotransposons encode noncanonical RRM domains in their first open reading frame. Proceedings of the National Academy of Sciences of the United States of America 106 (3), pp. 731 - 736 (2009)

Izaurralde, E.; Huntzinger, E.; Kashima, I.; Wittkopp, N.: SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoa. In The FEBS Journal, 276 (Supplement 1), IL 4.6–1, p. 37. 34th FEBS Congress, Prague, Czech Republic, July 04, 2009 - July 09, 2009. Wiley-Blackwell (2009)