Publications
^{_{Conservation of Protein Structure and Function}}

Kretsch, R.; Albrecht, R.; Andersen, E.; Chen, H.-A.; Chiu, W.; Das, R.; Gezelle, J.; Hartmann, M.; Höbartner, C.; Hu, Y. et al.; Jadhav, S.; Johnson, P.; Jones, C.; Koirala, D.; Kristoffersen, E.; Largy, E.; Lewicka, A.; Mackereth, C.; Marcia, M.; Nigro, M.; Ohja, M.; Piccirilli, J.; Rice, P.; Shin, H.; Steckelberg, A.-L.; Su, Z.; Srivastava, Y.; Wang, L.; Wu, Y.; Xie, J.; Zwergius, N.; Moult, J.; Kryshtafovych, A.: Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers. Proteins: Structure, Function, and Bioinformatics 94 (1), pp. 51 - 78 (2026)

Hu, Y.; Schwab, S.; Qiu, K.; Zhang, Y.; Bär, K.; Reichle, H.; Panzera, A.; Lupas, A.; Hartmann, M.; Dame, R. et al.; Alva, V.; Hernandez Alvarez, B.: DNA Wrapping by a Tetrameric Bacterial Histone. Nature Communications 16, 11108 (2025)

Ullrich, T.; Pollmann, C.; Ritter, M.; Haaf, J.; Aghaallaei, A.; Tesakov, I.; Hatskovska, V.; El-Riz, M.; Maksymenko, K.; Kandabarau, S. et al.; Klimiankou, M.; Lengerke, C.; Welte, K.; Hernandez-Alvarez, B.; Müller, P.; Lupas, A.; Piehler, J.; Skokowa, J.; ElGamacy, M.: Tuning of G-CSFR signaling by de novo designed agonists. Molecular Therapy 33 (11), pp. 5741 - 5759 (2025)

Schwab, S.; Hu, Y.; Hernandez Alvarez, B.; Alva, V.; Dame, R.: Histone-mediated chromatin organization in prokaryotes and viruses. Trends in Biochemical Sciences 50 (8), pp. 695 - 706 (2025)

Borbaran Bravo, N.; Deordieva, E.; Doll, L.; ElGamacy, M.; Dannenmann, B.; Azevedo, J.; Iannuzzo, A.; Delafontaine, S.; Lehnerz, M.; Kolodziej, M. et al.; Hernandez-Alvarez, B.; Hellmuth, A.-S.; Findik, B.; Zakharova, V.; Bräuning, S.; Kandabarau, S.; Lengerke, C.; Feil, R.; Meytz, I.; Delon, J.; Templin, M.; Sturm, M.; Rieß, O.; Zeidler, C.; Welte, K.; Shcherbina, A.; Klimiankou, M.; Skokowa, J.: A New Severe Congenital Neutropenia Syndrome Associated with Autosomal Recessive COPZ1 Mutations. Blood 145 (20), pp. 2317 - 2335 (2025)

Schwab, S.; Hu, Y.; van Erp, B.; Kajili, M.; Hartmann, M.; Hernandez-Alvarez, B.; Alva, V.; Boyle, A.; Dame, R.: Histones and histone variant families in prokaryotes. Nature Communications 15 (1), 7950 (2024)

Hu, Y.; Schwab, S.; Deiss, S.; Escudeiro, P.; van Heesch, T.; Joiner, J.; Vreede, J.; Hartmann, M.; Lupas, A.; Hernandez Alvarez, B. et al.; Alva, V.; Dame, R.: Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending. Nucleic Acids Research 52 (14), gkae485, pp. 8193 - 8204 (2024)

Maksymenko, K.; Maurer, A.; Aghaallaei, N.; Barry, C.; Borbarán-Bravo, N.; Ullrich, T.; Dijkstra, T.; Hernandez-Alvarez, B.; Müller, P.; Lupas, A. et al.; Skokowa, J.; ElGamacy, M.: The design of functional proteins using tensorized energy calculations. Cell Reports Methods 3 (8), 100560 (2023)

Skokowa, J.; Hernandez Alvarez, B.; Coles, M.; Ritter, M.; Nasri, M.; Haaf, J.; Aghaallaei, N.; Xu, Y.; Mir, P.; Krahl, A.-C. et al.; Rogers, K.; Maksymenko, K.; Bajoghli, B.; Welte, K.; Lupas, A.; Müller, P.; ElGamacy, M.: A topological refactoring design strategy yields highly stable granulopoietic proteins. Nature Communications 13 (1), 2948 (2022)

Maiwald, S.; Heim, C.; Hernandez Alvarez, B.; Hartmann, M.: Correction to "Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay". ACS Medicinal Chemistry Letters 13 (1), pp. 148 - 149 (2021)

ElGamacy, M.; Hernandez Alvarez, B.: Expanding the versatility of natural and de novo designed coiled coils and helical bundles. Current Opinion in Structural Biology 68, pp. 224 - 234 (2021)

Hernandez Alvarez, B.; Skokowa, J.; Coles, M.; Mir, P.; Nasri, M.; Weidmann, L.; Rogers, K.; Welte, K.; Lupas, A.; Müller, P. et al.; ElGamacy, M.: Design of novel granulopoietic proteins by topological rescaffolding. PLoS Biology 18 (12), e3000919 (2020)

Maiwald, S.; Heim, C.; Hernandez Alvarez, B.; Hartmann, M.: Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay. ACS Medicinal Chemistry Letters 12 (1), pp. 74 - 81 (2020)

Heim, C.; Pliatsika, D.; Mousavizadeh, F.; Bär, K.; Hernandez Alvarez, B.; Giannis, A.; Hartmann, M.: De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives. Journal of Medicinal Chemistry 62 (14), pp. 6615 - 6629 (2019)

Hernandez Alvarez, B.; Bassler, J.; Lupas, A.: Structural diversity of coiled coils in protein fibers of the bacterial cell envelope. International Journal of Medical Microbiology 309 (5), pp. 351 - 358 (2019)

Adlakha, J.; Karamichali, I.; Sangwallek, J.; Deiss, S.; Bär, K.; Coles, M.; Hartmann, M.; Lupas, A.; Hernandez Alvarez, B.: Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles. Structure 27 (3), pp. 464 - 475 (2019)

Boichenko, I.; Bär, K.; Deiss, S.; Heim, C.; Albrecht, R.; Lupas, A.; Hernandez Alvarez, B.; Hartmann, M.: Chemical Ligand Space of Cereblon. ACS Omega 3 (9), pp. 11163 - 11171 (2018)

Boichenko, I.; Deiss, S.; Bär, K.; Hartmann, M.; Hernandez Alvarez, B.: A FRET-Based Assay for the Identification and Characterization of Cereblon Ligands. Journal of Medicinal Chemistry 59 (2), pp. 770 - 774 (2016)

Hartmann, M.; Mendler, C.; Bassler, J.; Karamichali, I.; Ridderbusch, O.; Lupas, A.; Hernandez Alvarez, B.: α/β coiled coils. eLife 5, e11861 (2016)

Hartmann, M.; Boichenko, I.; Coles, M.; Lupas, A.; Hernandez Alvarez, B.: Structural dynamics of the cereblon ligand binding domain. PLoS One 10 (5), e0128342 (2015)