Publications of E Izaurralde
All genres
Journal Article (80)
21.
Journal Article
57 (6), pp. 1074 - 1087 (2015)
Molecular architecture of 4E-BP translational inhibitors bound to eIF4E. Molecular Cell 22.
Journal Article
5, 4790 (2014)
4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation. Nature Communications 23.
Journal Article
21 (7), pp. 599 - 608 (2014)
An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay. Nature Structural and Molecular Biology 24.
Journal Article
54 (5), pp. 737 - 750 (2014)
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing. Molecular Cell 25.
Journal Article
28 (8), pp. 888 - 901 (2014)
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression. Genes and Development 26.
Journal Article
42 (8), pp. 5217 - 5233 (2014)
The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1. Nucleic Acids Research (London) 27.
Journal Article
27 (24), pp. 2628 - 2641 (2013)
The role of disordered protein regions in the assembly of decapping complexes and RNP granules. Genes and Development 28.
Journal Article
20 (11), pp. 1289 - 1297 (2013)
Structure and assembly of the NOT module of the human CCR4-NOT complex. Nature Structural and Molecular Biology 29.
Journal Article
27 (19), pp. 2125 - 2138 (2013)
The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2. Genes and Development 30.
Journal Article
41 (18), pp. 8692 - 8705 (2013)
miRISC recruits decapping factors to miRNA targets to enhance their degradation. Nucleic Acids Research (London) 31.
Journal Article
5 (3), pp. 360 - 373 (2013)
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins. Molecular Cell 32.
Journal Article
32 (7), pp. 1052 - 1065 (2013)
GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation. EMBO Journal 33.
Journal Article
10 (2), pp. 228 - 244 (2013)
NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain. RNA Biology 34.
Journal Article
41 (2), pp. 978 - 994 (2013)
The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets. Nucleic Acids Research (London) 35.
Journal Article
27 (2), pp. 211 - 225 (2013)
An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay. Genes and Development 36.
Journal Article
4 (12), a012328 (2012)
A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs. Cold Spring Harbor Perspectives in Biology 37.
Journal Article
19 (12), pp. 1324 - 1331 (2012)
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Nature Structural and Molecular Biology 38.
Journal Article
40 (21), pp. 11058 - 11072 (2012)
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex. Nucleic Acids Research (London) 39.
Journal Article
13 (8), pp. 662 - 663 (2012)
Elucidating the temporal order of silencing. EMBO Reports 40.
Journal Article
40 (12), pp. 5651 - 5665 (2012)
The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Nucleic Acids Research (London)