Publications of E Izaurralde

Tritschler, F.; Braun, J.; Eulalio, A.; Truffault, V.; Izaurralde, E.; Weichenrieder, O.: Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Molecular Cell 33 (5), pp. 661 - 668 (2009)

Eulalio, A.; Huntzinger, E.; Nishihara, T.; Rehwinkel, J.; Fauser, M.; Izaurralde, E.: Deadenylation is a widespread effect of miRNA regulation. RNA: A Publication of the RNA Society 15 (1), pp. 21 - 32 (2009)

Huntzinger, E.; Kashima, I.; Fauser, M.; Saulière, J.; Izaurralde, E.: SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA: A Publication of the RNA Society 14 (12), pp. 2609 - 2617 (2008)

Tritschler, F.; Eulalio, A.; Helms, S.; Schmidt, S.; Coles, M.; Weichenrieder, O.; Izaurralde, E.; Truffault, V.: Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes. Molecular and Cellular Biology (Washington, DC) 28 (21), pp. 6695 - 6708 (2008)

Jinek, M.; Eulalio, A.; Lingel, A.; Helms, S.; Conti, E.; Izaurralde, E.: The C-terminal region of Ge-1 presents conserved structural features required for P-body localization. RNA-A Publication of the RNA Society 14 (10), pp. 1991 - 1998 (2008)

Eulalio, A.; Huntzinger, E.; Izaurralde, E.: GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nature Structural and Molecular Biology 15 (4), pp. 346 - 353 (2008)

Eulalio, A.; Huntzinger, E.; Izaurralde, E.: Getting to the root of miRNA-mediated gene silencing. Cell 132 (1), pp. 9 - 14 (2008)

Tritschler, F.; Eulalio, A.; Truffault, V.; Hartmann, M.; Helms, S.; Schmidt, S.; Coles, M.; Izaurralde, E.; Weichenrieder, O.: A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. Molecular and Cellular Biology (Washington, DC) 27 (24), pp. 8600 - 8611 (2007)

Eulalio, A.; Rehwinkel, J.; Stricker, M.; Huntzinger, E.; Yang, S.-F.; Doerks, T.; Dorner, S.; Bork, P.; Boutros, M.; Izaurralde, E.: Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes and Development 2 (20), pp. 2558 - 2570 (2007)

Dorner, S.; Eulalio, A.; Huntzinger, E.; Izaurralde, E.: Delving into the diversity of silencing pathways. Symposium on MicroRNAs and siRNAs: biological functions and mechanisms. EMBO Reports 8 (8), pp. 723 - 729 (2007)

Behm-Ansmant, I.; Kashima, I.; Rehwinkel, J.; Saulière, J.; Wittkopp, N.; Izaurralde, E.: mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons. FEBS Letters 581 (15), pp. 2845 - 2853 (2007)

Eulalio, A.; Behm-Ansmant, I.; Schweizer, D.; Izaurralde, E.: P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Molecular and Cellular Biology (Washington, DC) 27 (11), pp. 3970 - 3981 (2007)

Behm-Ansmant, I.; Gatfield, D.; Rehwinkel, J.; Hilgers , V.; Izaurralde, E.: A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay. EMBO Journal 26 (6), pp. 1591 - 1601 (2007)

Eulalio, A.; Behm-Ansmant, I.; Izaurralde, E.: P bodies: at the crossroads of post-transcriptional pathways. Nature Reviews Molecular Cell Biology 8 (1), pp. 9 - 22 (2007)

Glavan, F.; Behm-Ansmant, I.; Izaurralde, E.; Conti, E.: Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. EMBO Journal 25 (21), pp. 5117 - 5125 (2006)

Rehwinkel, J.; Raes, J.; Izaurralde, E.: Nonsense-mediated mRNA decay: Target genes and functional diversification of effectors. Trends in biochemical sciences 31 (11), pp. 639 - 646 (2006)

Behm-Ansmant, I.; Rehwinkel, J.; Doerks, T.; Stark, A.; Bork, P.; Izaurralde, E.: mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes and Development 20 (14), pp. 1885 - 1898 (2006)

Rehwinkel, J.; Natalin, P.; Stark, A.; Brennecke, J.; Cohen, S.; Izaurralde, E.: Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Molecular and Cellular Biology 26 (8), pp. 2965 - 2975 (2006)

Weigel, D.; Izaurralde, E.: A tiny helper lightens the maternal load. Cell 124 (6), pp. 1117 - 1118 (2006)

Behm-Ansmant, I.; Izaurralde, E.: Quality control of gene expression: a stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay. Genes and Development 20 (4), pp. 391 - 398 (2006)